Genome

google

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1920s: blend of gene and chromosome.

wiktionary

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From German Genom; gene +‎ -ome

etymonline

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genome (n.)

"sum total of genes in a set," 1930, genom, modeled on German genom, coined 1920 by German botanist Hans Winkler, from gen "gene" (see gene) + (chromos)om "chromosome" (see chromosome).