Annihilate
late Middle English (originally as an adjective meaning ‘destroyed, annulled’): from late Latin annihilatus ‘reduced to nothing’, from the verb annihilare, from ad- ‘to’ + nihil ‘nothing’. The sense ‘destroy utterly’ dates from the mid 16th century.
wiktionary
From Latin annihilō(“I reduce to nothing”), from ad(“to”) + nihil(“nothing”).
etymonline
annihilate (v.)
"reduce to nothing," 1520s, from Medieval Latin annihilatus, past participle of annihilare "reduce to nothing," from Latin ad "to" (see ad-) + nihil "nothing" (see nil). Related: Annihilated; annihilating.
Middle English had a past-participle adjective annichilate "destroyed, annulled, reduced to nothing" (late 14c.), from past participle of Old French anichiler "annihilate, destroy" (14c.) or the Medieval Latin verb.