Iota

google

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from Greek iōta . iota (sense 2) arose because iota is the smallest letter of the Greek alphabet: compare with jot.

wiktionary

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From Ancient Greek ἰῶτα(iôta), ultimately from Proto-Semitic *yad-(“hand”). Doublet of yodh.

etymonline

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iota (n.)

"very small amount," 1630s, figurative use of iota, ninth and smallest letter in the Greek alphabet (corresponding to Latin -i-). Its use in this sense is after Matthew v.18 (see jot (n.), which is the earlier form of the name in English), but iota in classical Greek also was proverbially used of anything very small. The letter name is from Semitic (compare Phoenician and Hebrew yodh).