Diseased

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Middle English (in the sense ‘lack of ease; inconvenience’): from Old French desaise ‘lack of ease’, from des- (expressing reversal) + aise ‘ease’.

wiktionary

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diseased ( comparative more diseased, superlative most diseased)

etymonline

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diseased (adj.)

"affected with a disease," late 15c., past-participle adjective from disease (v.).