Tweezers
mid 17th century: extended form of obsolete tweeze ‘case of surgical instruments’, shortening of etweese, anglicized plural of etui.
wiktionary
17th century (1645–55): plural of tweeser (on the model of nippers, pincers, pliers or scissors), from obsolete tweese(“case for small instruments”) (or alternatively, alteration of plural form tweeses), aphetic form of earlier etweese (plural of etwee), from French étuis, plural of étui(“case, box, cover”) (from Old French estui(“container, prison”, noun), derivative of étuier (earlier spelling, estuier(“to shut up, guard, keep, preserve, save, enclose, place in a cover”), probably from Vulgar Latin *estudiāre(“to keep, treat with care”) or *studiāre, from Latin studēre(“to care about”).
etymonline
tweezers (n.)
"small pincers, diminutive tongs," 1650s, extended from tweezes, plural of tweeze "case for tweezers" (1620s), a shortening of etweese, considered as plural of etwee (1610s) "a small case," from French étui "small case" (see etui). Sense transferred from the case to the implement inside it. For form, compare trousers from trouzes.